Nozim-2

Nozim 2® (Etizolam 2 mg) – Fast-Acting Relief for Anxiety and Panic Disorders

Nozim 2 is a high-potency, fast-acting anxiolytic medication formulated with 2 mg of Etizolam, a thienodiazepine derivative used for the short-term management of anxiety, panic attacks, and insomnia. Although structurally distinct from benzodiazepines, Etizolam acts on the same GABAergic system, producing similar calming, sedative, and anti-panic effects. Nozim 2 is especially effective in treating acute anxiety episodes, emotional instability, and tension-related sleep disturbances.

---

Therapeutic Class:

Thienodiazepines (Anxiolytic / Sedative-Hypnotic)

---

Indications:

• Generalized Anxiety Disorder (GAD)

• Panic Disorder (with or without agoraphobia)

• Short-term treatment of insomnia related to anxiety

• Situational anxiety or acute stress reactions

• Adjunct treatment in depression with anxiety symptoms

---

Mechanism of Action:

Etizolam enhances the binding of GABA to the GABA-A receptor complex, increasing chloride ion influx and neuronal hyperpolarization. This inhibitory action leads to CNS depression, resulting in anxiolytic, sedative, muscle relaxant, and mild anticonvulsant effects. Compared to traditional benzodiazepines, Etizolam may have a shorter half-life and reduced hangover effects.

---

Available Dosage Form:

• Tablets: 2 mg Etizolam per tablet

---

Common Side Effects:

• Drowsiness, fatigue

• Dizziness or loss of coordination

• Headache

• Muscle weakness

• Blurred vision

• Mild confusion or forgetfulness

*Note: These side effects are typically dose-dependent and reduce with continued or tapered use.

---

Precautions & Warnings:

• Dependence & Tolerance: Prolonged or high-dose use can lead to physical or psychological dependence.

• Withdrawal Risk: Stopping abruptly may cause rebound anxiety, tremors, irritability, or seizures.

• Avoid Alcohol: Co-use may result in dangerous CNS depression or respiratory issues.

• Caution While Driving: May impair concentration and coordination.

• Elderly Use: Use with caution; consider lower doses due to increased sensitivity.

---

Contraindications:

• Known hypersensitivity to Etizolam or related compounds

• History of substance abuse or dependency

• Severe hepatic impairment

• Myasthenia gravis

• Respiratory depression or sleep apnea

---

Storage Instructions:

• Store between 20°C to 25°C (68°F to 77°F)

• Protect from light, heat, and humidity

• Keep out of reach of children and unauthorized users

---

Note: Nozim 2® should only be prescribed by a licensed medical professional. It is intended for short-term use only and must not be taken without proper supervision. Misuse may lead to dependence, cognitive impairment, or serious withdrawal effects.